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Re:Launch HN: Fella (YC W20) – Tackling men's obesity using ... by noduerme on Saturday August 21, 2021 @10:41PM (#28262418)
That's what's known as an anecdote. This is what's known as a counterexample. And one thing is certain: No method has 100% success. To me the more important question isn't what percentage of cases something addresses, but whether it's a self fix where the benefits outweigh the risks. The risks of intermittent fasting are relatively low, and it may have side benefits like prolonged lifespan and slower telomere degradation as shown in animal models. The risks of essentially hacking your own insulin production to upregulate it if you're not diabetic are not nearly as well understood. On an individual basis, whatever gets you to where you're happy is great. Personally I've fasted every day my entire adult life and still have to work to keep weight off. But when someone puts a slick marketing package on fasting or drugs or surgery or anything else, I have to question whether they really have my best interests at heart. And usually the answer is obviously not.
Re:Launch HN: Fella (YC W20) – Tackling men's obesity using ... by nevinera on Saturday August 21, 2021 @10:45PM (#28262433)
I'm not arguing in favor of any particular approach (in particular the one posed by the original poster, which I have done zero research into). If and when they launch in a meaningful way I'll bother doing that research, but I am also a cynic about people offering to make a difficult thing easy for a recurring fee.
Re:Launch HN: Fella (YC W20) – Tackling men's obesity using ... by rich-cartwright on Sunday August 22, 2021 @12:28AM (#28262864)
Happy to help with any research if I can. A good starting point for the medication I referred to in my post is here: https://www.nejm.org/doi/full/10.1056/NEJMoa2032183
Re:Launch HN: Fella (YC W20) – Tackling men's obesity using ... by noduerme on Saturday August 21, 2021 @11:09PM (#28262538)
Sure. And well we should be. Identify what people view as a personal problem, then offer a solution. This is the second YC startup I've seen today that falls under the category of magic baldness cream.
Re:Launch HN: Fella (YC W20) – Tackling men's obesity using ... by rich-cartwright on Sunday August 22, 2021 @12:27AM (#28262860)
Guess I gotta step in here to protest "magic baldness cream".

We're not offering anything magic. The medication side has a compelling & growing evidence base: https://www.nejm.org/doi/full/10.1056/NEJMoa2032183

For the vast majority obesity doctors, a medication-assisted approach is now the gold standard.

The program side is also no magic. We do tough work, but with a strong evidence base, a powerful support structure and we give ourselves enough time (12-month program). We focus on the root causes of poor metabolic health: stress, sleep, exercise, dietary. From both the behavioral & psychological angles.

No magic here, just evidence-based interventions.