Calories are calories is much more true than people give it credit for. Here's a guy who ate nothing but twinkies and not only lost weight, but had all his health metrics improve: http://www.cnn.com/2010/HEALTH/11/08/twinkie.diet.professor/...

Human biodiversity is also much greater than most people give it credit for, and because of that, the fact that this one guy ate an all-Twinkie diet and became healthier is almost irrelevant - it's not even anecdata, because that would imply n>1.