CalyxOS on a Pixel 5 with microG for the past month. The only two problems I've had have been that I can't install the CapitalOne app and I can't install any paid Google store apps. I have a backup Android phone (Unihertz Jelly 2) with LineageOS and Google Play Services / Play Store installed, which I haven't had any issues with at all. I don't use Google Pay, Google Assistant or Google Maps. Those three apps are my biggest pain points, but a sacrifice I'm willing to make. I do use Garmin Pay on my Garmin watch and the Google Maps web app.