Ignoring WHO call, major nations stick to vaccine booster plans

Re:Ignoring WHO call, major nations stick to vaccine booster... by criticaltinker on Thursday August 05, 2021 @12:39PM (#28076122)

> The antibiotic resistance most likely predates widespread pharmacological usage

This is absolutely not true, see this very accessible peer-reviewed primary source for many historical examples of antibiotic resistance driven by modern medicine [1].

Here is an excerpt from [1]:

- "After a new drug is introduced, drug resistance can rapidly evolve, leading to treatment failures [12]. For instance, most Staphylococcus aureus isolates in British hospitals were resistant to penicillin just 6 years after the introduction of the drug [13]"

[1] Why does drug resistance readily evolve but vaccine resistance does not? https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2016...

[ Parent | on HN ]

Re:Ignoring WHO call, major nations stick to vaccine booster... by f6v on Friday August 06, 2021 @11:37AM (#28088630)

> This is absolutely not true

I’m not saying modern medicine didn’t put a ton of evolutionary pressure on antibiotic resistance. However, there’s some evidence of AR genes being present in the microbiomes of previously isolated tribes [1]. So we didn’t promote the “invention” of AR by bacteria, but likely just accelerated the selection of AR strains.

1. 10.1126/sciadv.1500183

[ Parent | on HN ]

Re:Ignoring WHO call, major nations stick to vaccine booster... by criticaltinker on Friday August 06, 2021 @12:50PM (#28089769)

I see, thanks for elaborating and providing the citation - very interesting paper indeed. "This is absolutely not true" was not a charitable/informed interpretation of your comment, my apologies.

> So we didn’t promote the “invention” of AR by bacteria, but likely just accelerated the selection of AR strains

Well put, we are in agreement.

[ Parent | on HN ]