It's all fun and games until you get a requirement that requires you to code. Now you have to code anyway, but using something that has 0.001% of the support online in terms of docos, solved problems, stackoverflow answers, and ongoing support from Oracle/MS/Facebook etc. of mainstream frameworks.

Bubble is great if you can't code and you want to save $5k on a developer (if the project is >$5k then its probably already too complex for no code!)