It would depend on your meaning. If you mean taking a device like a Dasung or a Onyx and connecting to the laptop and using it as another screen, then sure, that should work fine. If you mean taking out the LCD and popping in a raw eink panel, then no because they have different interfaces. Speaking of which, I don't see any clear specification on frame.work for the LCD connector or power specs.
I see they wrote on their blog.
" We don’t currently have plans for alternate displays, but we’ve designed the display to be easy to replace and the display connector on the mainboard to be able to support a broader range of possible displays. It’s unlikely we would go lower resolution in this form factor, but I agree there could be an interesting case for a display resolution that works at 2x scaling (at the tradeoff of battery life). "
But I couldn't easily find on their website the info for what type of connector and what type of power is delivered to it.