The XM4 has superior ANC to the Bose QC-35, but the Bose has a much more comfortable headband. Almost loose enough to feel like it’s going to fall off my head, but not quite.

I find that comfort is most definitely my biggest consideration, when we talk about the best headphones with ANC. Nothing else really matters too much if the thing hurts your head so much that you can’t wear them for long.