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Re:Cannabis first domesticated 12,000 years ago by neom on Sunday July 18, 2021 @09:30AM (#27872753)
Smoked weed every day for 10 years.

>I like weed as a productive drug, it's stronger than caffeine for me, but I develop tolerance and addiction quickly. Any solution to the tolerance problem? Quitting/breaks is obvious.

Switch strains frequently, try to find stuff far from the other.

>Is investing in weed stocks encouraging drug addiction/use? Is it ethical to promote drug use?

No, but also investing in weed stocks are probably not the best stocks you could invest in - that said: Invest in what you know!

>Is there a way to microdose? I'd like to be able to have tiny, controlled amounts every time.

Yes, but you'll have to take a huge long break to get your tolerance back down. Then make tea: https://www.thrillist.com/eat/nation/how-to-make-cannabis-te...

>Is there a solution to munchies?

Switch strains - tends to be more common in Indicas with a higher than normal CBD (or if you're into more "creative" solutions, low dose adderall with it, seems to balance out well in strains that cause munchies.)

>Has anyone been able to convince a fortune 500 company that they need(medical) marijuana for work? As mentioned I'm significantly more focused, but I don't like the social stigma. I already have the job, it's purely a cultural/social problem.

If you have a Drs note, there isn't much they can do.

> Are my memory problems due to weed or is this just age? (When not using) I feel like I've lost lots of childhood memories and I have more difficulty than ever with names.

I've read reports of this, I've anecdotally heard people say that - It's never been a problem for me (but aging certainly has)

>If my focus is better on weed, is there something else I can do for focus that isn't drug related?

Diaphragmatic breathing for 5 minutes when you find your mind wandering.

Re:Cannabis first domesticated 12,000 years ago by caymanjim on Sunday July 18, 2021 @12:29PM (#27874213)
Overall I agree with your comments.

> Switch strains - tends to be more common in Indicas with a higher than normal CBD

There is no scientific evidence backing up any claims about the effects of indica vs sativa, and no way to know which strain you're actually getting, even from dispensaries. They tend to be labeled according to the subjective experience of the person deciding how to label them. It's as meaningless as any other marketing label.

> If you have a Drs note, there isn't much they can do.

There's no federal protection, and state protections vary. Some states explicitly prohibit firing employees for off-duty medical marijuana use, but not all states with medical marijuana regulations have formal employee use regulations, and I don't think any have protections for recreational use. Additionally, even where medical use protections exist, they don't cover you being intoxicated on the job. There will be court cases that clarify all of this; meanwhile there's no definitive answer.

Re:Cannabis first domesticated 12,000 years ago by pmoriarty on Sunday July 18, 2021 @12:37PM (#27874299)
"There is no scientific evidence backing up any claims about the effects of indica vs sativa"

Though the research on this is also in its infancy, there has been speculation that the terpenes in cannabis play very important roles its effects.

I'm looking forward to the day when we can choose cannabis based on the various terpenes it contains, and not just on simplistic THC/CBD levels or indica/sativa distinctions.

Re:Cannabis first domesticated 12,000 years ago by grawprog on Sunday July 18, 2021 @01:17PM (#27874638)
>There is no scientific evidence backing up any claims about the effects of indica vs sativa, and no way to know which strain you're actually getting, even from dispensaries.

Even if it's the same strain cloned from the previous crop it can be different in THC/CBD content depending on growing conditions and a number of things. Even the harvest date, the drying and the curing process will affect the final product.

Re:Cannabis first domesticated 12,000 years ago by caymanjim on Sunday July 18, 2021 @01:35PM (#27874760)
I agree that there are different chemical constituents in different strains, that seem to--at least anecdotally--cause different subjective effects. I specifically take exception to the indica-vs-sativa claims, which appear to be complete nonsense, and aren't backed up by any science.
Re:Cannabis first domesticated 12,000 years ago by grawprog on Sunday July 18, 2021 @05:05PM (#27876663)
I was agreeing with you. I was just pointing out further, even exactly the same plant can have different chemical constituents based on a variety of things without even taking variations between different strains into account.
Re:Cannabis first domesticated 12,000 years ago by pmoriarty on Sunday July 18, 2021 @12:34PM (#27874265)
"If you have a Drs note, there isn't much they can do."

Many jobs require passing drug tests as a condition of employment.

It would be interesting to hear if anyone has challenged such tests by arguing their cannabis use was a medical necessity.

Re:Cannabis first domesticated 12,000 years ago by washadjeffmad on Sunday July 18, 2021 @04:28PM (#27876397)
Drug tests are not specific to metabolites only from scheduled sources. Because unscheduled cannabidiols trigger drug tests the same way as scheduled ones, they are ineffective at identifying illegal use.

And yes, this gets challenged frequently since there's a legal concentration of ∆9 for products sold in the US naturally derived from hemp.

Generally, if you weren't caught in possession of something scheduled, not admitting to use when presented with a "positive" drug test is enough to have it dismissed.

Re:Cannabis first domesticated 12,000 years ago by GravitasFailure on Sunday July 18, 2021 @03:07PM (#27875580)
I worked with two different people that tried that. First guy crashed a forklift and was told he couldn't operate heavy machinery while taking any kind of depressant medication, and the second one was an armed security guard who tried explaining that his paranoid behavior was from switching cannabis strains. Under federal law it's a felony to own or possess a firearm while a user of cannabis, and the court cases so far have not been friendly to medical users.