Re:Alphafold
by slownews45 on Thursday July 15, 2021 @04:15PM
(#27849554)
First seems reasonable. I've not heard of anything on the later coming even close credibly - though is an obvious holy grail.
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Re:Alphafold
by Duller-Finite on Thursday July 15, 2021 @09:59PM
(#27852311)
David Baker's group (author of the RoseTTAFold paper out today in science) has multiple exciting examples of de novo design of proteins.
For example, see [1] or [2], and [2] was spun off into a company (Neoleukin Therapeutics).
[1] https://science.sciencemag.org/content/371/6531/eabc8182 [2] https://www.nature.com/articles/s41586-018-0830-7