You will be lucky if they read your resume at all, and when they do, it'll likely be on their phone as they walk down the hall to the interview room.
Resumes are mostly to get past the HR filter, and maybe impress the hiring manager - the engineer interviewing cares how you perform in the room itself.
Also at a lot of big companies, interviewing is not for specific teams, so the odds of someone they haven't specifically headhunted ending up on their team is low.
As an aside, unlike other comments, I do read all resumes of candidates that make it to the interview stage in detail and ask questions about it to try and get a sense of whether there's any inflation going on or not.
I rarely look at resumes before I start the interview. Even if I did, I’m not going to peruse the candidate’s GitHub profile. The majority are pretty sparse or not relevant, and not worth the effort.
I wouldn't expect recruiters or hiring managers to be able to read code or appreciate its quality or complexity; but what about the engineers who conduct technical interviews? Would they not be interested to learn as much as they can about the candidate, especially if that candidate, if hired, will join their team?