Re:Burden of post-Covid-19 syndrome and implications for hea...
by heavyset_go on Tuesday July 13, 2021 @04:00PM
(#27825565)
> The only supplement/herbal medicine I've had success with is St. Johns Wort, but I've been strongly discouraged from using it by a psychiatrist who emphatically emphasized that an SSRI is a much safer and more controllable way to achieve the same effects if need be.
Yep. From Wikipedia[1]:
> On average, lead levels in women taking St. John's wort are elevated about 20%.
It's also a relatively dirty drug, with effects on typical monoamine and GABA reuptake, MAO-A and MAO-B inhibition and is an inhibitor or inducer at pretty much every relevant enzyme that breaks down common medications.
I wouldn't want to become dependent on something like that because the withdrawal syndrome could be pretty nasty compared to something relatively more selective and understood like an SSRI.
Even switching from SJW to something else might be tricky because of the enzyme induction.
Yep. From Wikipedia[1]:
> On average, lead levels in women taking St. John's wort are elevated about 20%.
It's also a relatively dirty drug, with effects on typical monoamine and GABA reuptake, MAO-A and MAO-B inhibition and is an inhibitor or inducer at pretty much every relevant enzyme that breaks down common medications.
I wouldn't want to become dependent on something like that because the withdrawal syndrome could be pretty nasty compared to something relatively more selective and understood like an SSRI.
Even switching from SJW to something else might be tricky because of the enzyme induction.
[1] https://en.wikipedia.org/wiki/Hypericum_perforatum#Antidepre...