If you're working on very slow network connections, or the network just dies entirely, it's not uncommon for Emacs just to hang entirely. You then have to kill Emacs from another terminal. At the time I was running exwm (an Emacs window manager), which made the whole thing even more painful. Emacs is powerful, but polish is not its strong point.

That said, this was a few years ago now. Things may have improved in 26.1 when threads were introduced, and async got even easier.