Pfizer creating booster targeting highly transmissible delta variant

Re:Pfizer creating booster targeting highly transmissible de... by jacksonkmarley on Friday July 09, 2021 @12:03PM (#27785112)

Anyone knowledgeable on vaccines care to comment on how compatible a booster shot would likely be with other types of vaccine?

While the first 2 shots were relatively close together the problems of brand-matching seem simpler than they would be many months later.

[ Parent | on HN ]

Re:Pfizer creating booster targeting highly transmissible de... by Exmoor on Friday July 09, 2021 @01:17PM (#27786026)

I believe all vaccines, other than 3 Chinese ones with names starting with "Sino", target the spike protein and all indications I've seen have been that two doses of different protein-targeting vaccines work well together.

The bigger issue would be if "Original Antigenic Sin" [0] could impact the immune systems response, but that would be part of the testing prior to releasing the booster I'm sure.

[0] https://en.wikipedia.org/wiki/Original_antigenic_sin

[ Parent | on HN ]

Re:Pfizer creating booster targeting highly transmissible de... by abystander on Friday July 09, 2021 @01:21PM (#27786073)

> The bigger issue would be if "Original Antigenic Sin" [0] could impact the immune systems response

presumably if this is an issue at all - it'd be because most people are "locked into" the spike protein as the original antigen, as opposed to those naturally infected and therefore carrying a immune repetoire against however many 10+ other proteins in sars-cov-2.

[ Parent | on HN ]