Note that intermixing between those whom we call 'Sub-Saharan' Africans and the "rest of the world" is definitely not new or unique to the 'Western Hemisphere' as OP seems to assume: we know very clearly from Classical written sources and iconography that there were many peoples of 'Sub-Saharan' appearance well north of the Sahara desert, in close contact with Mediterranean and Levantine (thus, clearly "Out of Africa") humans. Even more than this, we know of such 'Sub-Saharan' folks who were very deeply integrated in ancient Mediterranean and Levantine societies, and while these folks were clearly a tiny minority and their distinctive appearance was often remarked upon, this did not hurt their social standing in any sense; there was even a well-known Egyptian dynasty of "Black" pharaohs.