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Re:Psilocybin repairs 'brains cells damaged by depression' i... by sparkie on Wednesday July 07, 2021 @07:01AM (#27759619)
Dosage is usually measured in grams for the dried out mushrooms. There's no standard scale because the amount of psilocybin in each mushroom can vary quite a lot. Counter-intuitively, larger fruits tend to be less potent than smaller ones. The amount you take should depend on the kind of experience you want. Body weight shouldn't make a big difference. (These assume potent mushrooms such as Cubensis, Liberty Cap, Wavy Cap). Main effects kick in around 60-90 minutes after eating.

1/4-1/2g: microdose. You should still be able to function pretty normally on this.

1.0-1.5g: Recreational dose, lasting a couple of hours.

2.0-3.5g: Deep trip, lasting 3-6 hours.

4-5g+: Hero dose. Not recommended for beginners.

My first dose was 3.0g (cubensis) and it was great. I don't really see the point on microdosing and I see mushrooms as more medicine than a recreational drug. I usually take 3.5g as they're typically sold as 7g (1/4oz), which is 2 doses.

Re:Psilocybin repairs 'brains cells damaged by depression' i... by pps on Wednesday July 07, 2021 @06:00PM (#27766200)
How often do you take them? I have access all the time (hopefully dried P. cubensis are not toxic after months in a vacuum container), but they're not addicting and I keep forgetting about them :) My first dose was 7g (was supposed to be 4, but my old kitchen scale didn't measure properly) and I can assure everyone curious that it's not fun, lol
Re:Psilocybin repairs 'brains cells damaged by depression' i... by sparkie on Thursday July 08, 2021 @12:25PM (#27774213)
Around 2 or 3 times a year. Not took any for 8 months. I also use DMT occasionally. Last time was about 6 months ago.

I've had 7g myself and yeah, I wouldn't recommend it. 3.5g is enough.

Re:Psilocybin repairs 'brains cells damaged by depression' i... by jonkoops on Wednesday July 07, 2021 @07:30AM (#27759826)
In my experience it is better to measure the number of shrooms you are taking as the max. dose per shroom is pretty consistent vs. measuring the total weight.

If only Psilocybin was available as a substance so we could just measure μg directly.

Re:Psilocybin repairs 'brains cells damaged by depression' i... by sparkie on Wednesday July 07, 2021 @07:42AM (#27759923)
If you pick fresh this may be a good idea.

When you buy dried shrooms, it's not easy to tell what one fruit is because they shrivel up and break easily. Some sellers break them up deliberately - if some fruits are more potent than others, then by mixing them, the total psilocybin content is more likely to be similar in every package they sell.

Interestingly, some vendors sell "mushroom pills" and "mushroom chocolate bars," where they do this on a bigger scale - mill the mushrooms down into powder form and then thoroughly mix the powder to give an even distribution. The idea then is that each piece of chocolate in the bar contains the same amount of psilocybin - and with some trial and error taste testing, they can recommend how many pieces of chocolate to have for the desired effect. This also doesn't give you the same nausea you typically get by eating the dried mushrooms directly, which might give you a better trip.

Re:Psilocybin repairs 'brains cells damaged by depression' i... by pmoriarty on Wednesday July 07, 2021 @07:20AM (#27759747)
The strain of mushroom taken can also greatly influence the experience. Some strains are far more potent than others.