You'd probably do the same thing that you would do if they asked what a km was: keep changing the units until you get one that they recognise, and then now they can understand the original unit you used.
(Although in this specific case given that they're asking about the definition of the unit you'd probably provide that context without needing further prompting in the first place, similar to if they asked about the circumference of the earth and you gave an answer in metres)
It's roughly the same thing as describing a distant potentially-habitable planet as being "1.5 times the size of Earth" instead of giving its radius in metres. It's just that AUs wrap that "n times the distance between the sun and the earth" into a nice standardised unit.
The point would be to put it in a familiar unit, even though '150 million' isn't easy to visualize.