Yes. I’ve run the numbers several times. I have a 2 child family. Treating our house, child care, groceries, etc. as fungible I could take a 50% pay cut over SJC and “maintain” our quality of life on paper.
But details matter. I live in a community with 22 miles of maintained trail, some of the best school districts in the country (with no lottery system, we just pick a school), our grocery stores are better (better meat, better produce, better selection), etc.
After living both, I strongly suspect my current quality of life in PHX literally does not exist in the Bay Area no matter the price point.
To put in perspective of how little I pay, I pay about 1900/month for mortgage, taxes, insurance and HOA (which is like $150/month because we live in a gated area). I am about 30-45 minutes door to door from PHX airport.
On the low end, it would require ~75-80k before taxes just to make up the mortgage difference, and likely be more than that.
TL;DR: Yea, it can easily be 100k cheaper in PHX vs SF depending on your situation.