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A comment on What mRNA is good for, and what it maybe isn’t. Parent comment

Re:What mRNA is good for, and what it maybe isn’t by monocasa on Tuesday June 29, 2021 @07:16PM (#27682999)
What happens to the unactivated mRNA in that case? I was under the impression that it was typically the actual use of the mRNA by the ribosomes that broke them down generally, but I could be off base there.
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Re:What mRNA is good for, and what it maybe isn’t by gus_massa on Tuesday June 29, 2021 @07:25PM (#27683062)
The same mRNA can be used by multiple ribosomes. More info and "photos": https://biology.stackexchange.com/questions/54752/can-mrna-b...
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Re:What mRNA is good for, and what it maybe isn’t by monocasa on Tuesday June 29, 2021 @08:47PM (#27683660)
Sure, it isn't destroyed immediately and the mRNA is used multiple time, but that's still ultimately the ribosomes damaging the mRNA from use. My question is around how they break down if there aren't ribosomes involved (ie. if the capsules above aren't opened because they weren't exposed to the light trigger).
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Re:What mRNA is good for, and what it maybe isn’t by sudosysgen on Tuesday June 29, 2021 @10:13PM (#27684157)
Eventually the capsule will break down, be filtered out or be destroyed by the immune system and any RNA left will be broken down by RNAse.
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Re:What mRNA is good for, and what it maybe isn’t by gus_massa on Wednesday June 30, 2021 @08:36AM (#27687694)
More info about RNA destruction and RNAse https://en.wikipedia.org/wiki/Ribonuclease
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