Let's look at the first Wikipedia sentence on tyrosine kinase as a starting point:
"A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to the tyrosine residues of specific proteins inside a cell."
What's ATP? We both know what ATP is. Is ATP deeply part of metabolism? We both know it almost is a definition of metabolism. I want to shout at you. But I don't know who you are or how to connect with you.
Please, for the love of anything that you find Holy, instead of arguing with me on the internet do this: Read the books I recommended, and start looking for the links to metabolism like I just did for you instead of trying to "see DNA everywhere". You will go so much further and help all of us than just arguing with me.
As to the atp issue, yes it is involved with metabolism but so so much more. If you have time read The Biology if Cancer by R A Weinberg. He does a good job of exploring the historical investigations as wellas the science.
The DNA paradigm explains this very well. How does the book explain this treatment?
How about a stem cell transplant? Why do they cure certain cancers? Does the metabolism of the person donating their stem cells get taken up and adopted permanently by the recipient?