I find in simulation codes that lack of awareness of (a) is an absolute performance killer. Generally, it's better to use a pattern for an object that's a container for something - so don't have a 'Particle' object but a 'Particles' one that keeps things stores the properties of particles contiguously. In my old magnetics research area you have at least 8 and more frequently 10+ spatially varying parameters in double precision that you'd potentially need to store per particle/cell.