Re:Siberian cave hosted Neanderthals, Denisovans, and modern...
by topynate on Saturday June 26, 2021 @10:11AM
(#27642010)
> Is it simply that humans have about 30k genes, your children each only get half of your genes, and so after about 16 generations it is possible for someone to be a descendant of yours but not have any genes that came from you?
Yes, the difference between genealogical ancestry and genetic ancestry is just the reason. The modelling which gives those estimates for the IAP assumes very infrequent migrations of individuals – one per generation is enough. That level of migration would likely leave no genetic heritage at all. Probably many Africans have literally zero genetic inheritance from Neanderthals, but almost certainly those same Africans have Neanderthals in their ancestor tree, albeit through only a few lines of descent.
Re:Siberian cave hosted Neanderthals, Denisovans, and modern...
by nocut12 on Saturday June 26, 2021 @11:18AM
(#27642616)
I don't know enough about this to give a real answer, but there is some neanderthal ancestry in modern day African populations.
https://www.sciencemag.org/news/2020/01/africans-carry-surpr...
Re:Siberian cave hosted Neanderthals, Denisovans, and modern...
by klyrs on Saturday June 26, 2021 @11:11AM
(#27642538)
According to the wikipedia article you linked, those estimates were derived from simulations. I have trouble imagining that the simulations accurately model the diversity of human cultures, mating patterns, migration behaviors, etc. for the whole world over, spanning hundreds of thousands of years. If we sequenced the genome of every single person on earth, we'd still have trouble nailing down the truth because of various external sources of mutation, independent but identical mutation, etc.
People of Asian or European ancestry have 1-2% of their DNA from Neanderthals. People of African ancestry usually have no Neanderthal DNA.
But consider the identical ancestor point [1] (IAP) for humans. The IAP is the most recent point at which each individual then alive either (1) has zero now living descendants or (2) every now living person is one of their descendants.
Most estimates put the human IAP at less than 20k years ago (some estimates much less).
Neanderthals went extinct around 35k-50k years ago.
I have Neanderthal DNA (23andMe tells me I have 240 markers with at least one Neanderthal variant, about average for 23andMe customers). Therefore I have a Neanderthal ancestor who must have lived 35k or more years ago.
Unless the estimates of the human IAP are so far off that it was actually before my Neanderthal ancestor lived, I therefore must have an ancestor who was alive at the human IAP and who had Neanderthal DNA.
Since that ancestor of mine has at least one living descendant (me) and was alive at the IAP, everyone now alive must be a descendant of theirs. Thus I can conclude that everyone alive now has Neanderthal ancestry--including all those Africans with no Neanderthal DNA.
This at first seems contradictory, so what's the deal?
Is it simply that humans have about 30k genes, your children each only get half of your genes, and so after about 16 generations it is possible for someone to be a descendant of yours but not have any genes that came from you?
[1] https://en.wikipedia.org/wiki/Identical_ancestors_point