What you could do is to enumerate powers of the federal government, and one of those powers would be to “to regulate Commerce with foreign Nations, and among the several States”, with the understanding among the authors of the document that “regulating commerce” means regulating trade and tariffs, so that nobody then can misinterpret it as giving the federal power to regulate anything they want by arguing it affects interstate commerce.

They you're right back where you started: People fighting over enacting policies at the national level.