Was emailing involved? We've been getting so much support questions regarding encodings of HTML emails (we're a programmatic email service: http://mailgun.net) that we actually decided to become the first MTA to enforce utf-8 transcoding on the entire traffic: randomness in -> clean utf8 out and everyone is suddenly quiet&happy.

Something like this could be done as nginx/apache module: which detects encodings of the data and transcodes the HTML output into utf8 - could be useful for some cases.