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Re:The end of the pandemic is near by Retric on Wednesday May 26, 2021 @06:20PM (#27296832)
That study was not supposed to refer to viral load at initial infection, you need to test viral load at exposure in a lab.

The 1 vs 50 difference is known to be based in part on the innate immune system not just the adaptive immune system. Most of the time you don’t need to create specific antibodies etc. If only a single virus enters the body it’s likely for you to fight off the infection without noticing though with the downside of failing to develop long term immunity.

https://en.m.wikipedia.org/wiki/Innate_immune_system

The 50 vs 50,000 is a related though less proven idea. Extreme exposure can simply overwhelm the immune system and extreme cases directly result in septic shock, but the middle ground is harder to test.

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