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Re:The end of the pandemic is near by antibuddy on Wednesday May 26, 2021 @09:48AM (#27290445)
There are no long-term studies for mRNA vaccines.
Re:The end of the pandemic is near by m0llusk on Wednesday May 26, 2021 @02:22PM (#27294174)
That is not strictly speaking true. There have been no long term studies for the most recent mRNA vaccines, but mRNA technology has been in development for many years with much of the effort going into studies of human safety. This long period of development and testing is how the method of packaging the mRNA in a precisely engineered blob of fat came about.
Re:The end of the pandemic is near by loveistheanswer on Thursday May 27, 2021 @10:24AM (#27303511)
>mRNA technology has been in development for many years with much of the effort going into studies of human safety.

Have there been any long term human trials of mRNA vaccines?

Re:The end of the pandemic is near by m0llusk on Thursday May 27, 2021 @06:57PM (#27309641)
Yes, though that might depend on your definitions of both long term and vaccine. There is actually a quite interesting body of literature surrounding these developments, so it might be worth doing some searches and some reading.
Re:The end of the pandemic is near by loveistheanswer on Sunday May 30, 2021 @10:27AM (#27333462)
Do you have any sources for long term mRNA vaccine trials on humans?

My searches seem to indicate there are none, other than the preliminary, limited scope short term trials

Re:The end of the pandemic is near by gspr on Wednesday May 26, 2021 @10:42AM (#27291089)
So what? What's the mechanism you're concerned about?
Re:The end of the pandemic is near by loveistheanswer on Wednesday May 26, 2021 @12:20PM (#27292452)
>What's the mechanism you're concerned about?

What do you mean?

We can't know what the long term side effects of drugs are until we have long term data.

Even with long term data showing significant negative side effects of drugs, we often dont understand the "mechanism"

Re:The end of the pandemic is near by gspr on Wednesday May 26, 2021 @03:56PM (#27295312)
If the drug breaks down rapidly in the body, yes, we can indeed know that. Then there can be no mechanism by which it can have long term effects. That's what happens with the delivered mRNA.
Re:The end of the pandemic is near by soonnow on Wednesday May 26, 2021 @09:55PM (#27298481)
I'm fully for vaccination as I wrote above.

But out of interest, what about the people who have long-haul COVID, do we know the mechanism how they experience long term effects from the actual disease.

Would it be possible that vaccines created long-term effects in the same way?

Re:The end of the pandemic is near by loveistheanswer on Wednesday May 26, 2021 @06:36PM (#27296996)
What is the "mechanism" from the vaccine which has caused some people to get thrombocytopenia, bells palsy, temporary deafness, and other such side effects in just the short term?
Re:The end of the pandemic is near by gspr on Thursday May 27, 2021 @04:54AM (#27300727)
Hyperactive immune response gone wrong?
Re:The end of the pandemic is near by loveistheanswer on Thursday May 27, 2021 @10:22AM (#27303488)
Scientists don't know what causes auto immune reactions/disorders, or why they have seemingly been on the rise for decades.
Re:The end of the pandemic is near by phaemon on Wednesday May 26, 2021 @03:11PM (#27294785)
> What do you mean?

Apologies, don't mean to pick on you but wanted an example for a future comment.

This maintains context worse than GPT-3

Re:The end of the pandemic is near by grillvogel on Wednesday May 26, 2021 @01:54PM (#27293845)
"I've been smoking cigarattes for the past year and nothing bad has happened to me, i guess they are perfectly healthy"
Re:The end of the pandemic is near by soonnow on Wednesday May 26, 2021 @09:44PM (#27298413)
What about long-term studies for the actual COVID?