Re:CRISPR Editing in Primates
by sidlls on Thursday May 20, 2021 @10:06PM
(#27229746)
Vaccines, cancer treatements, anesthetics, and so on. Could some or many of these have been discovered without the use of animals in research? Perhaps--but hindsight is what it is, and I'd rather do research on animals with known and well-trod methodologies to discover these now in parallel with developing new techniques to make these discoveries without the use of animal models; not eschew the models until we have alternate methods.
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Re:CRISPR Editing in Primates
by teachingassist on Friday May 21, 2021 @09:00AM
(#27233457)
It's a matter of resources.
Animal testing has found hundreds of vaccines against HIV that work in primates, but none of them have worked in humans.
How is that a useful thing to spend time on? You have a model, and it's proven that your model doesn't work: I would expect you to throw away the model.
You could spend those excellent researchers and science budget on anything else, and expect better results.
(I get that all drugs have been tested on animals out of legislative requirement, but I hope it's clear we are talking about using animal models for de novo drug discovery).
For a business-oriented forum, I find it hard to understand why people see this as valuable.