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Re:CRISPR Editing in Primates by whymauri on Thursday May 20, 2021 @02:43PM (#27225341)
Did someone try editing out hERG?!
Re:CRISPR Editing in Primates by ellimilial on Thursday May 20, 2021 @02:52PM (#27225460)
A fair amount of drugs inhibiting it had to be recalled after https://pubmed.ncbi.nlm.nih.gov/16554806 and subsequent regulators actions.
Re:CRISPR Editing in Primates by whymauri on Thursday May 20, 2021 @03:02PM (#27225594)
Oh, OK -- right hERG inhibition liability is a candidate killer. It's just since the topic was gene editing, I thought someone had experimented with editing hERG somehow which had me really confused.