Dot-com bubble was real companies with inflated valuations from speculators and experimental business models that weren't all solvent.

Theranos was trying to make and sell a real product but the product didn't work so they lied and cheated to cover that up because they had nothing else to offer.

Every business is dreams and fairytales because extra sizzle gets more customers

It's different from cryptocurrencies which are pure scam plays from the start.