uBlock does detect this automatically, without reverse engineering your setup and adding it to their lists.

This assumes you self-host analytics.js and proxy GA API requests through your domain without changing path/query. If you manage to reverse engineer analytics.js and change the path/query AND proxy through your own domain, then this likely wouldn't be detected. But there's a chance that Google will make changes to analytics.js that aren't compatible with your reverse engineering it, and your setup breaks.