Plenty of us. While Node.js might not be talked about as much as Go or Rust is, it's battletested in my opinion and a breeze to work with. I'm currently using Node for a large-scale content platform that is comprised of an ingestion engine, a parser, a queue and scraper. 4 Node servers powering 40k+ sites, sitting behind a load balancer, NGINX and PostgreSQL. It's not using anything overly fancy, but is stable and easy to fix if anything goes wrong.