Re:Inflammation, but Not Telomere Length, Predicts Ageing at...
by DoreenMichele on Saturday April 17, 2021 @01:06AM
(#26841718)
It looks like it is actually a meta-analysis: A study of several other studies, which has good points and pitfalls.
we combined community-based prospective cohorts: Tokyo Oldest Old Survey on Total Health (TOOTH), Tokyo Centenarians Study (TCS) and Japanese Semi-Supercentenarians Study (JSS) comprising 1554 individuals including 684 centenarians and (semi-)supercentenarians, 167 pairs of centenarian offspring and spouses, and 536 community-living very old (85 to 99 years).
One of the good points is that it tends to include data from a great many more people than most studies can include. One of the pitfalls is that it is challenging to combine data from multiple studies because they probably used different methodologies, were measuring different things, etc and this puts a lot of noise in the data and cleaning the data to get something useful and meaningful can be quite hard.
Meta studies can be a case of "garbage in, garbage out." But when they are done well, they can roll up a whole lot of information together to draw conclusions we simply don't have the resources to meaningfully study some other way.
we combined community-based prospective cohorts: Tokyo Oldest Old Survey on Total Health (TOOTH), Tokyo Centenarians Study (TCS) and Japanese Semi-Supercentenarians Study (JSS) comprising 1554 individuals including 684 centenarians and (semi-)supercentenarians, 167 pairs of centenarian offspring and spouses, and 536 community-living very old (85 to 99 years).
One of the good points is that it tends to include data from a great many more people than most studies can include. One of the pitfalls is that it is challenging to combine data from multiple studies because they probably used different methodologies, were measuring different things, etc and this puts a lot of noise in the data and cleaning the data to get something useful and meaningful can be quite hard.
Meta studies can be a case of "garbage in, garbage out." But when they are done well, they can roll up a whole lot of information together to draw conclusions we simply don't have the resources to meaningfully study some other way.