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Re:US agencies call for pause in Johnson & Johnson vaccine by dheera on Tuesday April 13, 2021 @04:17PM (#26798622)
Yes, but 65% efficacy still means that 1/3 of the vaccinated people will continue to be spreaders, which doesn't sound great, especially if that allows the virus to spread and evolve into a harsher variety.
Re:US agencies call for pause in Johnson & Johnson vaccine by thelean12 on Tuesday April 13, 2021 @04:24PM (#26798740)
At this stage, getting as many people to near 100% death avoidance and with some immunity is the goal.

We're not at a stage yet when we can play favorites. It'll be a long time before we have the supply to prefer one over the other (except maybe in the US where there will be enough mRNA vaccines to go around).

Re:US agencies call for pause in Johnson & Johnson vaccine by M_bara on Tuesday April 13, 2021 @04:47PM (#26799058)
Not necessarily. Efficacy measures are about protection from hospitalisation or death if you contract COVID. It doesn’t imply loss of viral shedding. There’s a vox video on YouTube that explains this...
Re:US agencies call for pause in Johnson & Johnson vaccine by savanu on Tuesday April 13, 2021 @04:22PM (#26798697)
The different efficacy rates of the vaccines do not directly imply anything about spreading covid.

A vaccinated person can have no symptoms of covid and still be spreading (This may or may not be true).

Folks are still studying how effective the vaccines are at preventing spread.

Re:US agencies call for pause in Johnson & Johnson vaccine by cactus2093 on Tuesday April 13, 2021 @04:58PM (#26799204)
> A vaccinated person can have no symptoms of covid and still be spreading

Aren't the efficacy numbers from the phase 3 trials based on giving periodic PCR tests to everyone that was participating in the trials? And not just based on people self-reporting symptoms?

It would be very surprising if there were a new kind of asymptomatic carrier that emerged only for people having taken certain vaccines in which they would never test positive on a PCR test but could still spread covid. The odds that this is how the vaccines work seems very small, relative to the number of times this argument that "we don't know yet" is getting repeated.

It just seems strange to me that so many people are hung up on pointing out that this small possibility is still a possibility. It seems more likely that this will drive more people to skip the vaccine, since they're being told they can't even go back to normal once vaccinated, than anything else.

Re:US agencies call for pause in Johnson & Johnson vaccine by savanu on Tuesday April 13, 2021 @05:08PM (#26799347)
I don't think the fact that you might be still spreading covid when vaccinated is enough of a reason to continue lockdown. As long we are continually getting people vaccinated, we should be fine for returning to normal.
Re:US agencies call for pause in Johnson & Johnson vaccine by xiii1408 on Tuesday April 13, 2021 @06:06PM (#26799957)
Depends on the particular trial, but the clinical trial data used to get FDA approval usually measures symptomatic cases, which is a combination of coronavirus symptoms and positive PCR test.

There's some additional data which indicates Pfizer and Moderna are likely to limit transmission, but from my understanding it's not as ironclad as the symptomatic cases data.

Re:US agencies call for pause in Johnson & Johnson vaccine by DiogenesKynikos on Tuesday April 13, 2021 @05:42PM (#26799717)
> Aren't the efficacy numbers from the phase 3 trials based on giving periodic PCR tests to everyone that was participating in the trials?

For most trials, no. You have to look at each individual study, but most commonly, they only test after people show specific symptoms.

Re:US agencies call for pause in Johnson & Johnson vaccine by kazinator on Tuesday April 13, 2021 @04:23PM (#26798718)
Keep in mind that a door handle is completely immune to Covid and can be spreading it.
Re:US agencies call for pause in Johnson & Johnson vaccine by dheera on Tuesday April 13, 2021 @04:34PM (#26798884)
Only for a few hours though, not 2 weeks+, and viruses don't mutate on a doorknob. Someone who got vaccine and falls in the ineffective category will likely not die but will be a spreader for a few weeks, with some nonzero probability of mutation, and that times 1/3 of the population that got the vaccine would give the virus a lot of opportunity to mutate.
Re:US agencies call for pause in Johnson & Johnson vaccine by kazinator on Tuesday April 13, 2021 @04:44PM (#26799017)
According to some experts, Covid-19 can endure on certain surfaces for as long as six days.
Re:US agencies call for pause in Johnson & Johnson vaccine by dheera on Tuesday April 13, 2021 @04:24PM (#26798733)
Okay, but until they're done studying, maybe let's just make more of the 94% vaccine using J&J's facilities?
Re:US agencies call for pause in Johnson & Johnson vaccine by ghaff on Tuesday April 13, 2021 @04:35PM (#26798893)
You do realize that different manufacturing facilities are not interchangeable? They're not a rack of x86 servers.
Re:US agencies call for pause in Johnson & Johnson vaccine by stjohnswarts on Tuesday April 13, 2021 @07:17PM (#26800762)
Lol if the people that don't get it and it's more or less a cold it's not a big deal. If you go to the hospital your chances of dying from it go up astronomically. How can you miss that most basic of points?