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Re:Ask HN: What under-the-radar technology are you excited a... by pmarreck on Monday April 12, 2021 @06:20PM (#26785901)
Speaking as a very rational multiple-allergy sufferer (before 30? None. Then, like a dozen things!!) who has gotten allergy shots for years now...

Have any data to back up this substitute?

Also, Zyrtec and Claritin did nothing for me, I’m an Allegra guy

Re:Ask HN: What under-the-radar technology are you excited a... by ahstilde on Monday April 12, 2021 @11:47PM (#26787938)
Tons of data!

“Patients who have done [allergy drops] and finished a course are now free of taking any allergy medications and they don’t have symptoms anymore.” Dr. Sandra Lin, video interview, Sublingual Immunotherapy (SLIT) for Allergy Treatment: Johns Hopkins | Q&A, author of Efficacy and Safety of Subcutaneous and Sublingual Immunotherapy for Allergic Rhinoconjunctivitis and Asthma (2017)

Video: https://www.youtube.com/watch?v=dpWomI4iPLY Paper: https://pubmed.ncbi.nlm.nih.gov/28964530/

Aqueous allergy drops are both safe and effective for environmental allergies (aka allergic rhinitis): - This has been proven through 30 years of data published by leading allergists in key journals, and confirmed in 2011 independent Cochrane review Learn more: https://pubmed.ncbi.nlm.nih.gov/21154351/

Aqueous allergy drops have a better safety profile than allergy shots - Unlike shots, there has never been a documented fatality to allergy drops in 30 years of use - The risk of a systemic reaction is thought to be 1 per 100 million doses or 1 per 526,000 treatment years Learn more: https://pubmed.ncbi.nlm.nih.gov/22150126/

Allergy drops are equally as effective as allergy shots - They have widespread use in Europe (up to 80% of the immunotherapy market in some countries) - Comparison studies by leading allergists have shown both allergy shots and allergy drops to be effective but no clear superiority of one mode over the other. Learn more: https://pubmed.ncbi.nlm.nih.gov/23557834/ https://pubmed.ncbi.nlm.nih.gov/26853126/

Re:Ask HN: What under-the-radar technology are you excited a... by pmarreck on Thursday April 15, 2021 @02:21AM (#26816739)
Nice! I'm going to review this and see what my allergist says