This is a somewhat different category, vaccines that are supposed to direct antibodies against cancer tumors. The HPV/HBV ones are more traditional anti-viral vaccines that confer immunity to certain viruses, rather than specifically anti-cancer ones. They also have the effect of reducing cancer rates, since those viruses increase cancer rates, but only as a side-effect of preventing the viral infection.

Although, as another comment points out, even in the directly anti-cancer category this isn't actually the first; http://en.wikipedia.org/wiki/Sipuleucel-T is already approved.