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Re:South African variant can break through Pfizer vaccine, I... by tzs on Sunday April 11, 2021 @07:15AM (#26769451)
Is vaccine effectiveness per person or per infection opportunity?

In other words, does 95% effective mean that if you took a large group vaccinated people and once a day had an infected person have a massive coughing and sneezing fit right into their faces, 95% would never get infected by that and 5% would?

Or does it mean that they would all get infected, but it would take on average 20 times as long as it would have had they not been vaccinated?

Re:South African variant can break through Pfizer vaccine, I... by teeray on Sunday April 11, 2021 @08:33PM (#26774943)
It means that in the study submitted to the FDA, the vaccine group had 8 cases and the control group had 162 cases [0]. 8 / 162 = ~5% of the cases in the vaccine group, ergo 95% effectiveness (or more specifically Relative Risk Reduction).

[0] https://www.nejm.org/doi/full/10.1056/NEJMoa2034577