FDA approves first test of CRISPR for genetic defect causing sickle cell disease

Re:FDA approves first test of CRISPR for genetic defect caus... by farfalle on Thursday April 08, 2021 @09:21AM (#26738362)

Bone marrow transplant (BMT) recipients can still experience graft versus host disease (GVHD) which is when the transplanted marrow produces healthy cells that start to attack the host body.

Besides GVHD, it is like you said. BMT patients are one of the few transplant types that can eventually come off of immuno-suppressants with a successful transplant. The patient's original bone marrow is supposed to be wiped out by chemotherapy (and sometimes some radiation) to make room for the new marrow transplant.

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Re:FDA approves first test of CRISPR for genetic defect caus... by eganist on Thursday April 08, 2021 @10:37AM (#26739243)

Can we take a moment to appreciate the straightforward naming of graft-versus-host disease? I couldn't find the history of its discovery beyond this (https://www.sciencedirect.com/science/article/abs/pii/S03014...) and even there, I couldn't find any indication of how it came to receive that name specifically, but it's much better than "[scientist's name]'s disease/syndrome" that we keep running into because people want credits at the expense of accessibility of knowledge.

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