Ultimately, remote is likely going to win out. Most people in the white collar work force are older, have families and live in the burbs. The commute for a lot of them is 1+ hour each way.

But what you're saying is legitimate, and it bothers me the amount of people acting like it doesn't matter. American society already isolates people. Work is a big (maybe the biggest) avenue to develop friendships as an adult, just like school is when you're a kid. Not everybody gets married and then their life becomes about their 2 kids and any social interaction outside of that is incidental.