Sounds difficult if you want to replicate organs 1-1, but what makes sense for human/animal bodies isn't necessarily the best way for labs. Maybe a single large biochemical reactor can solve half of those issues? There are already well established procedures for growing cell cultures and multiple startups that want to grow muscles (meat) or other organs. I don't know details - not my field - but pretty sure a large part of those seemingly hard problems are already solved/worked around.