Loss of myelin is one of the major factors of age-related brain deterioration

Re:Loss of myelin is one of the major factors of age-related... by stevebmark on Tuesday March 16, 2021 @02:36AM (#26473685)

I would also avoid them because: https://pubmed.ncbi.nlm.nih.gov/7678175/

> Compared to a potent eukaryotic DNA topoisomerase type II poison ... ciprofloxacin produced comparable dose-dependent SCE frequency increases.

Translated: Compared to a chemotherapy drug designed to cause DNA breaks to prevent cell replication, ciprofloxacin produced similar "sister chromatid exchange" counts, which happen when damaged DNA strands need to pull in duplicate material from "sister" strands.

Counting SCEs is also used to measure human DNA mutations from things like carcinogens and radiation.

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Re:Loss of myelin is one of the major factors of age-related... by exikyut on Tuesday March 16, 2021 @04:19AM (#26474170)

Interesting. How is "counting SCEs" done?

A sibling comment (https://news.ycombinator.com/item?id=26473638) mentions the difficulty of acquiring pre-event context for these kinds of situations. Could this sort of testing be useful here?

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