A future civilization would need to reconstruct a compatible operating system, software and hardware first, then build something with a USB port to put the stick into.

It's not impossible but consider how many ancient human languages we still can't translate, or can only translate due to coincidence (as in the case of the Rosetta Stone with Egyptian hieroglyphics.) Translating digital information in a similar cultural vacuum would be exponentially more difficult. If that stick is encrypted, how does one even know there is information to begin with?