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Re:Over 140k virus species in the human gut, half of which a... by graeme on Monday March 08, 2021 @03:36PM (#26391159)
Ciprofloxacin? It has a black box warning from the FDA. Specifically for tendon issues.

“ Fluoroquinolones, including CIPRO®, are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants (see WARNINGS). Fluoroquinolones, including CIPRO, may exacerbate muscle weakness in persons with myasthenia gravis. Avoid CIPRO in patients with known history of myasthenia gravis (see WARNINGS).”

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/01...

All the quinolones also associated with lots of internet reports of ill health in a variety of respects, but tendinitis is the official warning.

Actually I see there is an updated warning about central nervous system damage now too. FDA recommends they only be used as a last resort.

Sorry you had that experience. I had Cipro about ten years ago, wasn’t really necessary. Can’t say for sure it did anything but my reaction was intense while on it, and I had much worsened general digestion and overall health after that point.

https://www.fda.gov/news-events/press-announcements/fda-upda...

Re:Over 140k virus species in the human gut, half of which a... by avgDev on Monday March 08, 2021 @04:09PM (#26391577)
I also had the pleasure of taking cipro about 10 years ago. Since, then I have met hundreds of people. Symptoms of adverse reaction include depression/anxiety, tendon/muscle pain, tendon ruptures, vision issues, such as visual snow and floaters. These issues are widely underreported as negative symptoms may show up even up to 12 months after medication was stopped.

I have seen 40+ physicians at Mayo, Rush and other popular hospital networks, only one doctor said it's a possibility. Others outright dismiss it and look for alternative diagnosis.

However, there are some recent discoveries and theories. There was a study which found DNA adducts from cipro, others are looking at mtDNA and collagen issues.

For anyone reading please research any flouroquinolone antibiotic before taking them. It is A SERIOUS medication and not like other antibiotics.

The worst part of FQAD (Flouroquinolone Associated Disability) as it is a thing now, there is ZERO tests to confirm it. If it happens to you, you will be dismissed and ignored by the medical community. I know doctors, pharmacists who had a negative reaction and were outright called crazy by their colleagues. An optometrist who was quite outspoken was dropped by some insurance companies as this view is "controversial". Many older flouroquinolone antibiotics have been taken off the market completely due to severe adverse reactions.

Re:Over 140k virus species in the human gut, half of which a... by graeme on Monday March 08, 2021 @09:23PM (#26394660)
> However, there are some recent discoveries and theories. There was a study which found DNA adducts from cipro, others are looking at mtDNA and collagen issues.

Have any links? And find anything that helped?

I’m doing much better than I was before. But not knowing whether the issues are due to Cipro I also can’t be sure that anything I tried addressed it.

Re:Over 140k virus species in the human gut, half of which a... by avgDev on Tuesday March 09, 2021 @10:11AM (#26399500)
A decent place to get information is a subreddit r/floxies. There isn't any treatments yet, however, magnesium seems to be a supplement that helps a lot of people. Check out the subreddit.
Re:Over 140k virus species in the human gut, half of which a... by tristor on Monday March 08, 2021 @04:46PM (#26392086)
I was prescribed Ciprofloxacin for traveler's diarrhea when I was traveling internationally for an extended period of time. I knew it was some hardcore stuff, so I didn't use it until it was a last resort. A single dose, and within 40 minutes I was experiencing neurological effects. I called a nurse-on-call and was told to discontinue. No permanent effects I know of, but it basically gave me temporary dementia. Definitely a medication that should come with stronger warnings. I know it's the only valid treatment for anthrax infections, but for general use it should not be prescribed.