So what? Does this mean I shouldn't be able to play with the big boys' toys? I certainly am not skilled enough to get to the break-even point where I earn back enough money to cover the cost of the program.
For me personally, if I was actually going to be using niche software like that to make things I was going to sell, I would not be comfortable doing it with pirated commercial software for both ethical and legal reasons, and I would look for adequate cheaper alternatives, only moving up to Altium when and if my sales justified it. This is why I don't actually own or use any Adobe software anymore -- it's less niche, to be sure, but I wouldn't use Photoshop and InDesign nearly enough to justify the price of Adobe Creative Suite. And, again, personally, I don't feel like "but I'd use them occasionally and I wanna use the big boys' toys" justifies me pirating Adobe's software rather than finding much cheaper alternatives that I still like.
As an aside, I've always found software at this price level to be a bit of a paradox when it comes to piracy -- Altium, Autodesk Maya ($1620/year, currently), and similarly priced vertical market solutions are big fish in tiny ponds. If you're in a business that needs Altium or Maya, you're almost certainly going to pay for it, and conversely, folks who pirate software like that almost certainly don't need it. If I ran such a software company I don't think I'd bother with DRM; your true copy protection dongle is (or at least better be!) the level of support you're giving licensed customers.