I have this running as a uBO scriptlet injected into every website before content javascript starts to execute

    *##+js(myscript)

does various things, disables webassembly, websocket, AudioContext, serviceworkers, openDatabase and indexedDB, navigator.sendBeacon and window.opener, some fingerprinting randomization stuff, etc. I wish there was a Browser on the market actually letting you configure such things _per domain_ as Opera Presto used to, alas we are on our own now :(.