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A comment on Mypyc: Compile type-annotated Python to C. Parent comment

Re:Mypyc: Compile type-annotated Python to C by averageuser on Tuesday February 23, 2021 @11:40AM (#26239373)
Cython lets you use C structs to speed up memory access, and generally gives you lower-level access.

Note that GraalPython has the C structs memory layout too.

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