While not completely customizable, it is already configurable. The Alexa/Echo devices currently support 4 wake words - Alexa, Amazon, Computer, and Echo.

I work with an Aleksa that I refer to frequently during calls, and was quite excited when I stumbled on the wake word setting in the Alexa app.

You can change it to Amazon, Echo, or Computer. None of which are likely to be names of people in your house--other than the Dollhouse exception for Echo. Most people just likely prefer a more personal name which is, almost by definition, an accepted human name.

Computer is great because it reminds me of Star Trek.