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Re:How Antidepressants Work, at Last? by sjg007 on Friday February 19, 2021 @05:09PM (#26198671)
This is fascinating. Cholesterol has long be associated with depression.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606915/

Re:How Antidepressants Work, at Last? by momszack on Friday February 19, 2021 @05:23PM (#26198802)
That associates statin use with depression, not cholesterol. That’s a huge difference. Those results (which are not an RCT) could easily be explained by those that are less depressed are more likely to seek any non-psychiatric outside medical treatment.
Re:How Antidepressants Work, at Last? by m00x on Friday February 19, 2021 @06:27PM (#26199451)
First: cholesterols are a family of molecules, like alcohols, not just one thing.

Second: statins inhibit cholesterols so while it is associated, it's good to mention that cholesterols are anti-depressive, which is something anyone with any university bio education will know.