Fuel budget = magazine depth. It takes more missiles to shoot down missiles, does not favor defense. Every missile designed for intercept is one less missile in inventory for attack. Forcing missiles off course is going to become increasingly difficult as kill chain condenses, the more loop shift towards onboard sensors the more difficult to disrupt.

UAVs are potentially just larger missiles with more fuel and ability to out maneuver smaller missiles, made more difficult with addition maneuverability when biologic limitations removed. I imagine scenario converging to large performant UAVs with high performance envelopes trained to dodge anti air-missiles with relative impunity, shifting battle space to mutual air supremacy and race to destroy asset fastest. Essentially the end of hegemony via naval force projection.