Half Doses of Moderna Vaccine Produce Neutralizing Antibodies

Re:Half Doses of Moderna Vaccine Produce Neutralizing Antibo... by tmzt on Sunday February 14, 2021 @02:46PM (#26135551)

This may be true, but isn't vaccine fundamentally a delivery mechanism for a custom mRNA strand?

If you build up the infrastructure you could quickly deliver a vaccine for another disease or practically any genetic therapy that could be delivered the same way. Moderna also has an advantage in that the logistics required are simpler.

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Re:Half Doses of Moderna Vaccine Produce Neutralizing Antibo... by ch4s3 on Sunday February 14, 2021 @07:08PM (#26137541)

The mixing step ins't transferable. I'm not super familiar with micro fluid mixing, but it happens on specially created glass plates with channels as narrow as a molecule wide. They's essentially single purpose physical process microchips. Constructing them is a (maybe the) bottle neck. Apparently you can count on both hands the number of people who know how to build these things.

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Re:Half Doses of Moderna Vaccine Produce Neutralizing Antibo... by tmzt on Monday February 15, 2021 @03:34AM (#26140456)

Interesting. Are these channels related to length (in bases) of certain components?

What is the basis for saying the vaccine were developed "in a day" if this crucial, specific step was required?

Are there good sources with details on those steps and microfluidic chips?

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