> I currently use a tenkeyless keyboard which gives me the only less-than-fullsize keyboard advantage that I care about: my mouse is closer.

FINALLY an advantage to my "handicap": I use the numeric keypad somewhat frequently, and the additional size of the keyboard doesn't bother me at all. The number pad could be as large as another full-size keyboard, and my mouse wouldn't be a nanometre further away. And ever since I bought my left-handed mouse, it's comfortable and ergonomic and whatnot, too.