Re:18.7 Million Americans Vaccinated
by AndrewBissell on Monday January 25, 2021 @01:54AM
(#25900134)
W.r.t. vitamin D I was referring to supplementation to prevent deficiency in the first place, not to administering shots as treatment to desperately try and get the levels back up once an infection reaches an advanced state.
I find any "the required dose for in vitro neutralization is too high" reasoning to be dubious for the simple reason that we are not trying to battle the virus in vitro. A good meta-analysis on ivermectin: https://www.researchsquare.com/article/rs-148845/v1 There are also some accounts of possible successful use as prophylactic in Chiapas and India but I'm not familiar with any studies on that subject.
I don't really feel any cognitive dissonance in observing that the same TPTB (if you prefer that term to "they") which clearly strongly desires that everyone gets a jab is not necessarily all that competent at running the administration and logistics side, particularly not on the enormously compressed timescales which have characterized Operation Warp Speed.
Japan used to be included in the usual lists of "here's how it's done" countries until they had some relatively significant community spread this winter. New Zealand has been in their summer but just reported their first case of community spread in months as their autumn gets underway -- being an easily isolated island I imagine they might have more success keeping things under control, but if Covid goes endemic I don't expect lockdowns to halt it in its tracks there any better than they have in the US or Europe. I don't buy China's numbers given that they have laughably reported a single Covid-19 death for a country of 1.4B people in the last 8 months, and find including them on a list characterized by "minimal invasion of peoples' freedom" bizarre.
I find any "the required dose for in vitro neutralization is too high" reasoning to be dubious for the simple reason that we are not trying to battle the virus in vitro. A good meta-analysis on ivermectin: https://www.researchsquare.com/article/rs-148845/v1 There are also some accounts of possible successful use as prophylactic in Chiapas and India but I'm not familiar with any studies on that subject.
HCQ appears effective when combined with a TMPRSS2 inhibitor: https://journals.plos.org/plospathogens/article?id=10.1371/j...
In the vaccine trial, when suspected COVID cases are included (they dwarfed the confirmed positive tests used in the 95% number), the effectiveness estimate drops to 19%-29%: https://blogs.bmj.com/bmj/2021/01/04/peter-doshi-pfizer-and-...
I don't really feel any cognitive dissonance in observing that the same TPTB (if you prefer that term to "they") which clearly strongly desires that everyone gets a jab is not necessarily all that competent at running the administration and logistics side, particularly not on the enormously compressed timescales which have characterized Operation Warp Speed.
Japan used to be included in the usual lists of "here's how it's done" countries until they had some relatively significant community spread this winter. New Zealand has been in their summer but just reported their first case of community spread in months as their autumn gets underway -- being an easily isolated island I imagine they might have more success keeping things under control, but if Covid goes endemic I don't expect lockdowns to halt it in its tracks there any better than they have in the US or Europe. I don't buy China's numbers given that they have laughably reported a single Covid-19 death for a country of 1.4B people in the last 8 months, and find including them on a list characterized by "minimal invasion of peoples' freedom" bizarre.